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1

ApoE and Clusterin Cooperatively Suppress Aβ Levels and Deposition: Evidence that ApoE Regulates Extracellular Aβ Metabolism In Vivo

Ronald B DeMattos, John R Cirrito, Maia Parsadanian, Patrick C May, Mark A O'Dell, Jennie W Taylor, Judith A.K Harmony, Bruce J Aronow, Kelly R Bales, Steven M Paul, David M Holtzman

Journal:

Year:

2004

Language:

english

File:

PDF, 304 KB

english, 2004

2

A Practical Guide to the Management of Hypertension in Renal Transplant Recipients

Ali J. Olyaei, Angelo M. deMattos, Dr William M. Bennett

Journal:

Year:

1999

Language:

english

File:

PDF, 249 KB

english, 1999

3

Human apoE Isoforms Differentially Regulate Brain Amyloid- Peptide Clearance

Castellano, J. M., Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman

Journal:

Science Translational Medicine

Year:

2011

Language:

english

File:

PDF, 476 KB

english, 2011

4

Decision making in trauma centers from the standpoint of complex adaptive systems

Ribeiro Soriano, Domingo, deMattos, Policarpo C., Miller, Daniel M., Park, Eui H.

Journal:

Management Decision

Year:

2012

Language:

english

File:

PDF, 425 KB

english, 2012

5

A γ-secretase inhibitor decreases amyloid-β production in the central nervous system

Randall J. Bateman, Eric R. Siemers, Kwasi G. Mawuenyega, Guolin Wen, Karen R. Browning, Wendy C. Sigurdson, Kevin E. Yarasheski, Stuart W. Friedrich, Ronald B. DeMattos, Patrick C. May, Steven M. Pau

Journal:

Annals of Neurology

Year:

2009

Language:

english

File:

PDF, 737 KB

english, 2009

6

Reply

Randall J. Bateman, Eric R. Siemers, Kwasi G. Mawuenyega, Wendy C. Sigurdson, Kevin E. Yarasheski, Stuart W. Friedrich, Ron B. DeMattos, Patrick C. May, Steven M. Paul, David M. Holtzman

Journal:

Annals of Neurology

Year:

2010

Language:

english

File:

PDF, 65 KB

english, 2010

7

In situ AFM studies of astrocyte-secreted apolipoprotein E- and J-containing lipoproteins

Justin Legleiter, Ronald B. DeMattos, David M. Holtzman, Tomasz Kowalewski

Journal:

Journal of Colloid and Interface Science

Year:

2004

Language:

english

File:

PDF, 592 KB

english, 2004

8

Ziprasidone and the activity of cytochrome P450 2D6 in healthy extensive metabolizers

K. D. Wilner, S. B. Demattos, R. J. Anziano, G. Apseloff, &amp, , N. Gerber

Journal:

British Journal of Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 73 KB

english, 2000

9

Plaque-associated disruption of CSF and plasma amyloid-β (Aβ) equilibrium in a mouse model of Alzheimer's disease

Ronald B. DeMattos, Kelly R. Bales, Maia Parsadanian, Mark A. O'Dell, Eric M. Foss, Steven M. Paul, David M. Holtzman

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 274 KB

english, 2002

10

Cadaver kidney transplantation in patients more than 65 years old

J. M. Barry, M. J. Lemmers, M. M. Meyer, A. DeMattos, W. M. Bennett, D. J. Norman

Journal:

World Journal of Urology

Year:

1996

Language:

english

File:

PDF, 544 KB

english, 1996

11

New pathways in drug discovery for alzheimer’s disease

Eric R. Siemers, Robert A. Dean, Ronald Demattos, Patrick C. May

Journal:

Current Neurology and Neuroscience Reports

Year:

2006

Language:

english

File:

PDF, 120 KB

english, 2006

12

A liver X receptor and retinoid X receptor heterodimer mediates apolipoprotein E expression, secretion and cholesterol homeostasis in astrocytes

Yu Liang, Suizhen Lin, Thomas P. Beyer, Youyan Zhang, Xin Wu, Kelly R. Bales, Ronald B. DeMattos, Patrick C. May, Shuyu Dan Li, Xian-Cheng Jiang, Patrick I. Eacho, Guoqing Cao, Steven M. Paul

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 452 KB

english, 2004

13

Migratory movements of waterfowl in Central Asia and avian influenza emergence: sporadic transmission of H5N1 from east to west

SAMUEL A. IVERSON, ANDREI GAVRILOV, TODD E. KATZNER, JOHN Y. TAKEKAWA, TRICIA A. MILLER, WARD HAGEMEIJER, TAEJ MUNDKUR, BALACHANDRAN SIVANANINTHAPERUMAL, CARLOS C. DeMATTOS, LU’AY S. AHMED, SCOTT H. N

Journal:

Year:

2011

Language:

english

File:

PDF, 724 KB

english, 2011

14

The impact of hepatitis C virus infection on renal allograft recipients

Roth, David, Zucker, Keith, Cirocco, Robert, DeMattos, Angelo, Burke, George W, Nery, Jose, Esquenazi, Violet, Babischkin, Sharon, Miller, Joshua

Journal:

Kidney International

Year:

1994

Language:

english

File:

PDF, 757 KB

english, 1994

15

Chronic cyclosporine nephropathy: The Achilles' heel of immunosuppressive therapy

Bennett, William M, DeMattos, Angelo, Meyer, Mary M, Andoh, Takeshi, Barry, John M

Journal:

Kidney International

Year:

1996

Language:

english

File:

PDF, 1.31 MB

english, 1996

16

Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model

Dodart, Jean-Cosme, Bales, Kelly R., Gannon, Kimberley S., Greene, Stephen J., DeMattos, Ronald B., Mathis, Chantal, DeLong, Cynthia A., Wu, Su, Wu, Xin, Holtzman, David M., Paul, Steven M.

Journal:

Nature Neuroscience

Year:

2002

Language:

english

File:

PDF, 354 KB

english, 2002

17

Apolipoprotein E dose-dependent modulation of β-amyloid deposition in a transgenic mouse model of Alzheimer’s disease

Ronald B. DeMattos

Journal:

Journal of Molecular Neuroscience

Year:

2004

Language:

english

File:

PDF, 90 KB

english, 2004

18

Midlife Blood Pressure, Plasma -Amyloid, and the Risk for Alzheimer Disease: The Honolulu Asia Aging Study

Shah, N. S., Vidal, J.-S., Masaki, K., Petrovitch, H., Ross, G. W., Tilley, C., DeMattos, R. B., Tracy, R. P., White, L. R., Launer, L. J.

Journal:

Year:

2012

Language:

english

File:

PDF, 806 KB

english, 2012

19

Interaction Between Tacrolimus and Nefazodone in a Stable Renal Transplant Recipient

Ali J. Olyaei, Angelo M. DeMattos, Douglas J. Norman, William M. Bennett

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

1998

Language:

english

File:

PDF, 347 KB

english, 1998

20

Behavioral and neurochemical changes in the dopaminergic system after repeated cocaine administration

Lynne H. Claye, Hyacinth C. Akunne, M. Duff Davis, Steve DeMattos, Karam F. A. Soliman

Journal:

Molecular Neurobiology

Year:

1995

Language:

english

File:

PDF, 1.24 MB

english, 1995

21

Characterization of the human dopamine D3 receptor expressed in transfected cell lines

Robert G. MacKenzie, Donald VanLeeuwen, Thomas A. Pugsley, Yu-Hsin Shih, Steve Demattos, Lei Tang, Richard D. Todd, Karen L. O'Malley

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1994

Language:

english

File:

PDF, 674 KB

english, 1994

22

Alzheimer’s Aβ vaccination of rhesus monkeys (Macaca mulatta)

Sam Gandy, Ron B DeMattos, Cynthia A Lemere, Frank L Heppner, Jodi Leverone, Adriano Aguzzi, William B Ershler, Jinlu Dai, Paul Fraser, Peter St George Hyslop, David M Holtzman, Lary C Walker, Evan T

Journal:

Mechanisms of Ageing and Development

Year:

2004

Language:

english

File:

PDF, 52 KB

english, 2004

23

Aβ immunization and anti-Aβ antibodies: potential therapies for the prevention and treatment of Alzheimer’s disease

David M Holtzman, Kelly R Bales, Steven M Paul, Ronald B DeMattos

Journal:

Advanced Drug Delivery Reviews

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

24

Association of CD20+ Infiltrates with Poorer Clinical Outcomes in Acute Cellular Rejection of Renal Allografts

Benjamin E. Hippen, Angelo DeMattos, William J. Cook, Clifton E. Kew II, Robert S. Gaston

Journal:

American Journal of Transplantation

Year:

2005

Language:

english

File:

PDF, 199 KB

english, 2005

25

Lack of correlation between ACAT mRNA expression and cholesterol esterification in primary liver cells

Thomas J. Rea, Ronald B. DeMattos, Reynold Homan, Roger S. Newton, Michael E. Pape

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1996

Language:

english

File:

PDF, 782 KB

english, 1996

26

Agonist properties of a stable hexapeptide analog of neurotensin, NαMeArg-Lys-Pro-Trp-tLeu-Leu (NT1)

Hyacinth C. Akunne, Steven B. Demattos, Steven Z. Whetzel, David J. Wustrow, Duff M. Davis, Lawrence D. Wise, Wayne L. Cody, Thomas A. Pugsley, Thomas G. Heffner

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 1013 KB

english, 1995

27

Effect of Different Anti-Aβ Antibodies on Aβ Fibrillogenesis as Assessed by Atomic Force Microscopy

Justin Legleiter, Dan L. Czilli, Bruce Gitter, Ronald B. DeMattos, David M. Holtzman, Tomasz Kowalewski

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 2.75 MB

english, 2004

28

Production and characterization of astrocyte-derived human apolipoprotein E isoforms from immortalized astrocytes and their interactions with amyloid-β

Masayuki Morikawa, John D. Fryer, Patrick M. Sullivan, Erin A. Christopher, Suzanne E. Wahrle, Ronald B. DeMattos, Mark A. O'Dell, Anne M. Fagan, Hilal A. Lashuel, Thomas Walz, Kiyofumi Asai, David M.

Journal:

Neurobiology of Disease

Year:

2005

Language:

english

File:

PDF, 801 KB

english, 2005

29

Aβ immunotherapy: Translation of preclinical biomarkers into the clinic

Ronald DeMattos

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 66 KB

english, 2009

30

Use of A2 kidneys for B and O kidney transplant recipients: report of a series of patients transplanted at a single center spanning a decade

D.J Norman, J.C Prather, A.M Alkhunaizi, A.M deMattos, M Golconda, J.M Barry

Journal:

Transplantation Proceedings

Year:

2001

Language:

english

File:

PDF, 62 KB

english, 2001

31

The impact of generic drugs on the cost of transplantation medical care

A.J Olyaei, A.M deMattos, W.M Bennett

Journal:

Transplantation Proceedings

Year:

1999

Language:

english

File:

PDF, 74 KB

english, 1999

32

Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice

Ronald B DeMattos, Robert P Brendza, John E Heuser, Malca Kierson, John R Cirrito, John Fryer, Patrick M Sullivan, Anne M Fagan, Xianlin Han, David M Holtzman

Journal:

Neurochemistry International

Year:

2001

Language:

english

File:

PDF, 688 KB

english, 2001

33

Role of APOE in Alzheimer's disease-like neurodegeneration

David M. Holtzman, Anne M. Fagan, Kelly R. Bales, Ronald DeMattos, Michael C. Irizarry, Karen H. Ashe, Bradley T. Hyman, Steven M. Paul

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 396 KB

english, 2000

34

Analysis of cerebrospinal fluid beta-amyloid and apolipoprotein E lipoproteins in APPV717F transgenic mice

Ronald B. DeMattos, Kelly R. Bales, Steven M. Paul, David M. Holtzman

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 182 KB

english, 2000

35

O1-03-04 The LDL receptor regulates levels of CNS and Alzheimer's disease-like pathology

John D. Fryer, Ronal B. DeMattos, Mark A. O'Dell, Michael L. Spinner, Kelly R. Bales, Steven M. Paul, Maia Parsadanian, Guojun Bu, David M. Holtzman

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 321 KB

english, 2004

36

P1-240 Static and dynamic AFM studies of β-amyloid aggregates and their interaction with relevant biological macromolecules

Justin Legleiter, Dan L. Czilli, Bruce Gitter, Ronald B. DeMattos, Dave M. Holtzman, Tomasz Kowalewski

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 160 KB

english, 2004

37

Experimental utility of rabies virus-neutralizing human monoclonal antibodies in post-exposure prophylaxis

C.A Hanlon, C.A DeMattos, C.C DeMattos, M Niezgoda, D.C Hooper, H Koprowski, A Notkins, C.E Rupprecht

Journal:

Year:

2001

Language:

english

File:

PDF, 103 KB

english, 2001

38

Evidence for peripheral clearance of cerebral Aβ protein following chronic, active Aβ immunization in PSAPP mice

Cynthia A Lemere, Edward T Spooner, John LaFrancois, Brian Malester, Chica Mori, Jodi F Leverone, Yasuji Matsuoka, Jennie W Taylor, Ronald B DeMattos, David M Holtzman, John D Clements, Dennis J Selko

Journal:

Neurobiology of Disease

Year:

2003

Language:

english

File:

PDF, 459 KB

english, 2003

39

Safety and biomarker effects of solanezumab in patients with Alzheimer’s disease

Martin Farlow, Steven E. Arnold, Christopher H. van Dyck, Paul S. Aisen, B. Joy Snider, Anton P. Porsteinsson, Stuart Friedrich, Robert A. Dean, Celedon Gonzales, Gopalan Sethuraman, Ronald B. DeMatto

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 570 KB

english, 2012

40

A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice

DeMattos, Ronald B., Lu, Jirong, Tang, Ying, Racke, Margaret M., DeLong, Cindy A., Tzaferis, John A., Hole, Justin T., Forster, Beth M., McDonnell, Peter C., Liu, Feng, Kinley, Robert D., Jordan, Will

Journal:

Year:

2012

Language:

english

File:

PDF, 1.91 MB

english, 2012

41

Expression of acyl-coenzyme A:cholesterol acyltransferase (ACAT) mRNA in the rabbit

P.A. Schultz, R.A. DeMattos, T.J. Rea, R.S. Newton, B.R. Krause, M.E. Pape

Journal:

Atherosclerosis

Year:

1994

Language:

english

File:

PDF, 156 KB

english, 1994

42

O4-03-04: Safety assessments and biomarker changes following a monoclonal Aβ antibody given to subjects with Alzheimer’s disease

Eric R. Siemers, Charles Benson, Celedon Gonzales, Ryan Hansen, Robert A. Dean, Martin R. Farlow, Ronald DeMattos

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

43

P2-026: The cholesterol transporter ABCG1 modulates the proteolytic processing of amyloid precursor protein

Gavin Tansley, Braydon L. Burgess, Matt Bryan, Yuan Su, Jeniffer Y. Chan, Kathryn E. Naus, Sean McIsaac, Veronica Hirsch-Reinshagen, Hsui-Chiung Yang, Ronald B. DeMattos, Cheryl L. Wellington

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 68 KB

english, 2006

44

Measurement of cerebrospinal fluid total tau and phospho-tau in phase 2 trials of therapies targeting Aβ

Eric R. Siemers, Robert A. Dean, D.R. Lachno, Joseph J. Zajac, Gopalan Sethuraman, Ronald B. DeMattos, Patrick C. May

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 45 KB

english, 2009

45

ELISA-based measurement of plasma total Aβ1-40 and Aβ1-42, and CSF total and free Aβ1-40 and Aβ1-42 in the presence of solanezumab, a mid-domain anti-A beta antibody

Robert A. Dean, Ronald DeMattos, Valentina Gelfanova, John Hale, Richard Lachno, Margret Racke, Jayne Talbot, Eric Siemers

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 44 KB

english, 2009

46

Identification, characterization, and comparison of amino-terminally truncated Aβ42 peptides in Alzheimer's disease brain tissue and in plasma from Alzheimer's patients receiving solanezumab immunotherapy treatment

Ronald B. DeMattos, Margaret M. Racke, Valentina Gelfanova, Beth Forster, Michael D. Knierman, Matthew T. Bryan, John E. Hale, Robert A. Dean, Steven M. Paul, Eric R. Siemers

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 110 KB

english, 2009

47

Soluble Aβ clearance from the brain interstitial fluid of PDAPP mice is human apoE isoform-dependent

Joseph M. Castellano, Floy R. Stewart, Patrick C. May, Ronald B. DeMattos, Steven M. Paul, David M. Holtzman

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 52 KB

english, 2010

48

Characterization of novel apoE isoform-dependent C-terminal specific proteolysis of Aβ1-42 by microglia

Feng Liu, Suizhen Lin, Xiyun Chai, Ronald B. DeMattos, Steven M. Paul, Eli Lilly

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 40 KB

english, 2010

49

Heterogeneity of plasma beta-amyloid species before and after treatment with solanezumab

Ronald DeMattos

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 94 KB

english, 2012

50

14-117 - Lack of CYP 2D6 inhibition by ziprasidone in healthy volunteers

K.D. Wilner, S.B. DeMattos, R.J. Anziano, G. Apseloff, N. Gerber

Journal:

Biological Psychiatry

Year:

1997

Language:

english

File:

PDF, 280 KB

english, 1997